Testing for the safety and efficacy of Power Plus™ (poly-enzyme supplement) on patients with Irritable Bowel Syndrome
Study type: A multi-centered, prospective, randomized, double-blind, placebo-controlled study on the safety and efficacy of the poly-enzyme supplement Power Plus for patients with Irritable Bowel Syndrome (IBS). An independent peer review will follow before publication in a prominent medical journal. Reprints will be available upon completion of the trial.
Objectives: Test the efficacy and safety of a poly-enzyme supplement by assessing the following symptoms and physical findings: abdominal pain, bloating, constipation, diarrhea, and mucus with bowel movements. In addition, the following laboratory test was measured: CBC (Complete blood count).
Materials and methods: Sixty subjects from two centers underwent randomization and were divided into two groups to receive either the active investigational product (Power Plus) or a placebo with a non-active recipient. The 500 mg veggie capsules were administered in the following amounts: 2 at breakfast, 3 at lunch, and 4 at dinner. The duration of the study trial was 90 days. Patients were screened to meet the inclusion and exclusion criteria for the study protocol. Three follow-up visits were scheduled at weeks 4, 8, and 12 to ascertain the subjects’ symptoms and physical findings.
Conclusion: Power Plus demonstrated a significant improvement in reducing the above-stated symptoms and physical findings at the clinical trial’s completion. Moreover, investigators found no reports of adverse events from the ingestion of the investigational product.
Study Investigators
Nasser Hajjar, MD, Internal Medicine, Gastroenterologist
American University of Beirut, Beirut, Lebanon
Mike Hung, MD, Ph.D., Internal Medicine, Gastroenterologist
Hubei Medical University, China
Roger Patick, MD, Internal Medicine, Gastroenterologist
University of Montreal, Canada.
Charlie Khano, MD, Internal Medicine
Durango Medical Group, Denver, Colorado
Phillip Shinnick, D.C., Ph.D., NY, NY
The Research Institute of Global Physiology, Behavior & Treatment
Cindy Maloore, Ph.D., Nutritionist
Private Practice, Santa Clara, CA
Carol Poppay, Chief Nurse
Intel Corporation, Santa Clara, CA